A cell-permeable inhibitor of caspase-3 activation; blocks apoptosis in a variety of cell lines induced by different stimuli

M50054 – 5 mg

Brand:
Cayman
CAS:
54135-60-3
Storage:
-20
UN-No:
Non-Hazardous - /

M50054 is a cell-permeable inhibitor of the activation of caspase-3, blocking characteristic features of apoptosis, including DNA fragmentation and externalization of phosphatidylserine.{32778} It blocks apoptosis in a variety of cell lines induced by different stimuli, including Fas ligand and etoposide (Item No. 12092).{32778} M50054 has been used to inhibit apoptosis in skin, Xenopus larvae, teleost fish, and planaria, particularly in the context of tissue regeneration.{32774,32775,32777,32776}  

 

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Description

A cell-permeable inhibitor of caspase-3 activation; blocks apoptosis in a variety of cell lines induced by different stimuli, including Fas ligand and etoposide

Formal name: 2,2′-methylenebis-1,3-cyclohexanedione

Synonyms: 

Molecular weight: 236.3

CAS: 54135-60-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Inhibitors|Caspases||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases

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