An activator of PLC that stimulates superoxide generation

m-3M3FBS – 25 mg

Brand:
Cayman
CAS:
200933-14-8
Storage:
-20
UN-No:
Non-Hazardous - /

m-3M3FBS is an activator of phospholipase C (PLC) that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 µM.{27909} It stimulates cytoplasmic calcium increases in several cell lines and, at 25 µM in vitro, promotes the hydrolysis of phosphatidylinositol bisphosphate by all PLC isoforms.{27909} m-3M3FBS is used to study PLC signaling in cells and animals, often in conjunction with the PLC inhibitor U-73122 (Item No. 70740).{27905,27907,27908}  

 

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Description

An activator of PLC that stimulates superoxide generation, increase in cytoplasmic calcium, and inositol phosphate formation in human neutrophils when used at a concentration of 15-50 µM; promotes the hydrolysis of phosphatidylinositol bisphosphate by all PLC isoforms

Formal name: 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]-benzenesulfonamide

Synonyms: 

Molecular weight: 343.4

CAS: 200933-14-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Lipases||Research Area|Cell Biology|Cell Signaling|Calcium Mobilization||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases

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