An activator of glucokinase (EC50 = 42 nM); stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM); decreases plasma glucose levels in a dose-dependent manner in fasted rats (30 mg/kg)

LY2608204 – 25 mg

Brand:
Cayman
CAS:
1234703-40-2
Storage:
-20
UN-No:
Non-Hazardous - /

LY2608204 is an activator of glucokinase (GK; EC50 = 42 nM).{41671} It stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM). LY2608204 (30 mg/kg) decreases plasma glucose levels in a dose-dependent manner in fasted rats.  

 

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SKU: 22914 - 25 mg Category:

Description

An activator of glucokinase (EC50 = 42 nM); stimulates glucose metabolism in INS-1E rat insulinoma cells (mean EC50 = 579 nM); decreases plasma glucose levels in a dose-dependent manner in fasted rats (30 mg/kg)

Formal name: (1R,2S)-2-cyclohexyl-1-[4-(cyclopropylsulfonyl)phenyl]-N-[5-[[2-(1-pyrrolidinyl)ethyl]thio]-2-thiazolyl]-cyclopropanecarboxamide

Synonyms: 

Molecular weight: 559.8

CAS: 1234703-40-2

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Nutrient Sensing

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