Description
LSD1 is a flavin-containing nuclear protein having a N-terminal SWIRM domain, a C-terminal FAD-binding motif, and an amine oxidase domain. It functions as a transcriptional corepressor and catalyzes the flavin-dependent demethylation of Lys4 of histone 3 resulting in the formation of methyl-free lysine and release of formaldehyde. LSD1 has been found to be typically associated with CoREST and histone deacetylases 1 and 4 and participates in the silencing of endogenous neuron-specific genes.
Synonyms: Amine Oxidase (flavin containing) Domain 2
Immunogen: peptide corresponding to a portion of human LSD1 amino acids 100-150
Formulation: 100 µg of peptide affinity-purified IgG in 200 µl PBS containing 0.2% gelatin and 0.05% sodium azide
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Epigenetics, Transcription, & Translation|Erasers|Histone Demethylation
