Description
Lysophosphatidic acid receptor 3 (LPA3, also known as EDG-7) is one of three LPA receptors (LPA1, LPA2, and LPA3) that are members of large family of G protein-coupled receptors that also include those for sphingosine-1-phosphate (S1P1-5).{11049} The LPA receptors mediate many cellular responses including cytoskeletal rearrangements, cell proliferation, and inhibition of gap junction communication.{11808,11809} Mouse and human LPA3 have 353 amino acids with an estimated molecular weight of 40 kDa.{11811,11810} The mRNA level of LPA3 is high in testes, kidney, and lung but low in intestine, heart, thymus, and stomach.{11810} Cayman Chemical’s LPA3 polyclonal antibody can be used for western blot, immunofluorescence, and immunocytochemical analysis for LPA3 on samples of human, mouse, and rat origin. Cayman’s LPA3 Polyclonal Antibody detects a protein at around 40 kDa in human HepG2 cells, mouse macrophages, and in mouse and rat liver.
Synonyms: EDG-7|Lysophosphatidic Acid Receptor 3
Immunogen: Synthetic peptide from the N-terminal region of mouse protein LPA3
Formulation: 500 µl of peptide affinity-purified antibody
Isotype:
Applications: ICC, IF, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunocytochemistry||Application|Immunofluorescence||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|ECM & Adhesion Molecules
