A flavonoid with diverse biological activities; inhibits xanthine oxidase (IC50 = 37.4 µg/ml) and scavenges DPPH hydroxy

Lonicerin – 500 µg

Brand:
Cayman
CAS:
25694-72-8
Storage:
-20
UN-No:
Non-Hazardous - /

Lonicerin is a flavonoid that has been found in L. japonica and has diverse biological activities, including antioxidant, anti-inflammatory, and neuroprotective properties.{45090,45091,45092} Lonicerin inhibits xanthine oxidase (IC50 = 37.4 µg/ml) and scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805), hydroxyl, and superoxide radicals (IC50s = 9.2, 236.8, and 143.9 µg/ml, respectively).{45091} It reduces paw edema in a mouse model of C. albicans cell wall- and complete Freund’s adjuvant-induced arthritis when administered at doses of 1 and 2 mg/kg three times every other day.{45090} It also decreases nitric oxide (NO) production and T cell proliferation in vitro when used at concentrations of 20 and 40 µg/ml, respectively. Lonicerin is neuroprotective against glutamate-induced neurotoxicity in rat primary cortical neurons.{45092}  

 

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SKU: 25148 - 500 µg Category:

Description

A flavonoid with diverse biological activities; inhibits xanthine oxidase (IC50 = 37.4 µg/ml) and scavenges DPPH hydroxy, and superoxide radicals (IC50s = 9.2, 236.8, and 143.9 µg/ml, respectively); reduces paw edema in a mouse model of C. albicans cell wall- and complete Freund’s adjuvant-induced arthritis at 1 and 2 mg/kg three times every other day; decreases NO production and T cell proliferation in vitro at 20 and 40 µg/ml; neuroprotective against glutamate-induced neurotoxicity in rat primary cortical neurons

Formal name: 7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-5-hydroxy-4H-1-benzopyran-4-one

Synonyms:  Veronicastroside

Molecular weight: 594.5

CAS: 25694-72-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Neuroscience|Neuroprotection||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Xanthine Oxidase

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