A flavonoid with diverse biological activities; inhibits corticosterone-induced apoptosis in PC12 cells at 1 and 2 mg/ml; reduces spinal cord levels of IL-1β

Liquiritin – 5 mg

Brand:
Cayman
CAS:
551-15-5
Storage:
-20
UN-No:
Non-Hazardous - /

Liquiritin is a flavonoid that has been found in Glycyrrhiza and has diverse biological activities.{53639,53640,53641} It inhibits corticosterone-induced apoptosis in PC12 cells when used at concentrations of 1 and 2 mg/ml.{53639} Liquiritin (120 mg/kg) reduces spinal cord levels of IL-1β, IL-6, and TNF-α and alleviates mechanical and cold allodynia, as well as thermal hyperalgesia, in a mouse model of neuropathic pain induced by chronic constriction injury (CCI) of the sciatic nerve.{53640} It decreases the viability of SiHa, CaSki, and HeLa cervical cancer cells and inhibits migration and invasion of SiHa cells in vitro when used at concentrations of 40, 60, and 80 μM.{53641} Liquiritin (10, 20, and 30 mg/kg) reduces tumor growth in a SiHa mouse xenograft model.  

 

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SKU: 30263 - 5 mg Category:

Description

A flavonoid with diverse biological activities; inhibits corticosterone-induced apoptosis in PC12 cells at 1 and 2 mg/ml; reduces spinal cord levels of IL-1β, IL-6, and TNF-α and alleviates mechanical and cold allodynia, as well as thermal hyperalgesia, in a mouse model of neuropathic pain induced by CCI of the sciatic nerve at 120 mg/kg; decreases the viability of SiHa, CaSki, and HeLa cervical cancer cells and inhibits migration and invasion of SiHa cells in vitro at 40, 60, and 80 μM; reduces tumor growth in a SiHa mouse xenograft model at 10, 20, and 30 mg/kg

Formal name: (2S)-2-[4-(β-D-glucopyranosyloxy)phenyl]-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one

Synonyms: 

Molecular weight: 418.4

CAS: 551-15-5

Purity: ≥98%

Formulation: A solid

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