An internal standard for the quantification of Lipoxin A4 by GC- and LC-MS

Lipoxin A4-d5 – 25 µg

Brand:
Cayman
CAS:
1622429-53-1
Storage:
-80
UN-No:
De Minimis - 1170 / 3

Lipoxin A4-d5 (LXA4-d5) contains five deuterium atoms at the 19, 19’, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of LXA4 by GC- or LC-mass spectrometry (MS). LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes.{352} LXA4 is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 µM.{350} LXA4 is associated with several other biological functions including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.{350,354,2722}  

 

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SKU: 10007737 - 25 µg Category:

Description

An internal standard for the quantification of Lipoxin A4 by GC- and LC-MS

Formal name: 5S,6R,15S-trihydroxyicosa-7E,9E,11Z,13E-tetraenoic-19,19,20,20,20-d5 acid​

Synonyms:  5(S),6(R),15(S)-TriHETE-d5|5(S),6(R)-LXA4-d5

Molecular weight: 357.5

CAS: 1622429-53-1

Purity: ≥99% deuterated forms (d1-d5)

Formulation: A solution in ethanol

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Lipids|Lipoxins/Resolvin Es||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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