Description
A flavonoid glycoside with diverse biological activities; potentiates TRAIL-induced cytotoxicity and apoptosis in U87MG human glioma cells; potentiates TRAIL-induced tumor cell apoptosis and reduction of tumor growth in a U87MG mouse xenograft model; reduces pulmonary platelet count, edema, and macrophage, polymorphonuclear leukocyte, and lymphocyte infiltration, as well as inhibits TXNIP/NLRP3, MAPK, and NF-κB signaling in a mouse model of LPS-induced acute lung injury from 12.5-50 mg/kg; inhibits AChE and induces dyskinesia recovery in a zebrafish model of Alzheimer’s disease in tank water at 50 μg/ml
Formal name: 7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
Synonyms: Acacetin 7-O-rutinoside|Acaciin|Buddleoflavonoloside|Buddleoside|Linarigenin glycoside
Molecular weight: 592.6
CAS: 480-36-4
Purity: ≥95%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Natural Products|Glycosides||Product Type|Biochemicals|Small Molecule Inhibitors|Acetylcholine Turnover||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Immunology & Inflammation|Pulmonary Diseases||Research Area|Neuroscience|Neurodegenerative Disorders|Alzheimer’s Disease
