A monocyclic monoterpene with diverse biological activities; inhibits the growth of bacteria including S. aureus

(+)-Limonene – 1 mg

Brand:
Cayman
CAS:
5989-27-5
Storage:
-20
UN-No:
- 2052 / 3

(+)-Limonene is a monoterpene that has been found in citrus oils and Cannabis and has diverse biological activities, including anticancer, antimicrobial, antioxidant, anti-inflammatory, and chemoprotective properties.{34447,34446,36762,36763} It inhibits the growth of bacteria including S. aureus, B. cereus, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, M. catarrhalis, and C. neoformans with MIC values ranging from 3 to 27 mg/ml.{34447} In a human BGC-823 gastric cancer nude mouse orthotopic transplantation model, (+)-limonene inhibits tumor growth by 47.6% compared to controls and reduces the number of metastases in the liver, peritoneum, and other organs when administered by gastric perfusion at a dose of 15 ml/kg of a 1% emulsion.{34445} Dietary administration of (+)-limonene (5 and 10% in chow) reverses doxorubicin-induced decreases in glutathione (GSH) levels in rat kidney.{36762} Formulations containing (+)-limonene have been used as flavoring and fragrance agents and in the treatment of gallstones, heartburn, and gastroesophageal reflux disorder.  

 

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Description

A monocyclic monoterpene with diverse biological activities; inhibits the growth of bacteria including S. aureus, B. cereus, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, M. catarrhalis, and C. neoformans (MICs = 3-27 mg/ml); inhibits tumor growth and reduces the number of metastases in the liver, peritoneum, and other organs in a human BGC-823 gastric cancer nude mouse orthotopic transplantation model at 15 ml/kg of a 1% emulsion; reverses doxorubicin-induced decreases in GSH levels in rat kidney at 5 and 10% in the diet

Formal name: 1-methyl-4R-(1-methylethenyl)-cyclohexene

Synonyms:  (+)-Dipentene|(R)-(+)-Limonene|D-Limonene

Molecular weight: 136.2

CAS: 5989-27-5

Purity: ≥98%

Formulation: A neat oil

Application||Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Phytocannabinoids||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur|Glutathione

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