LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL.{379

Leukotriene B4 dimethyl amide – 25 µg

Brand:
Cayman
CAS:
83024-92-4
Storage:
-20
UN-No:
De Minimis - 1230 / 3|6.1

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL.{379,384,1106} LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.{1106}  

 

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Description

LTB4 dimethyl amide is a moderate inhibitor of LTB4-induced degranulation of human neutrophils (Ki = 130 nM) and lysozyme release from rat PMNL.{379,384,1106} LTB4 dimethyl amide appears to be an antagonist of the LTB4 receptor on guinea pig lung membranes.{1106}

Formal name: N,N-dimethyl-5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenamide

Synonyms:  LTB4 dimethyl amide

Molecular weight: 363.5

CAS: 83024-92-4

Purity: ≥97%

Formulation: A solution in methanol

Product Type|Biochemicals|Lipids|Leukotrienes||Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Leukotrienes||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Lipoxygenase Pathways

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