A small molecule inhibitor of human cytomegalovirus viral replication (EC50 = ~5 nM with a selectivity index >15

Letermovir – 1 mg

Brand:
Cayman
CAS:
917389-32-3
Storage:
-20
UN-No:
Non-Hazardous - /

Letermovir is a small molecule inhibitor of human cytomegalovirus viral replication (EC50 = ~5 nM with a selectivity index >15,000) that targets viral DNA cleavage and packaging.{28506,28505} It functions to prevent viral DNA concatemers from forming the proper unit length and interferes with virion maturation.{28505}  

 

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Description

A small molecule inhibitor of human cytomegalovirus viral replication (EC50 = ~5 nM with a selectivity index >15,000) that targets viral DNA cleavage and packaging

Formal name: (4S)-8-fluoro-3,4-dihydro-2-[4-(3-methoxyphenyl)-1-piperazinyl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4-quinazolineacetic acid

Synonyms:  AIC246

Molecular weight: 572.6

CAS: 917389-32-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases

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