The hydrochloride of leelamine

Leelamine (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
16496-99-4
Storage:
-20
UN-No:
Non-Hazardous - /

Leelamine is a diterpene molecule whose name derives from the Sanskrit word leela which means “play”. It has weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM.{14127} Leelamine inhibits pyruvate dehydrogenase kinase (PDK) with an IC50 of 9.5 µM.{14105} Derivatives of leelamine exhibit anti-inflammatory activity and show moderate inhibition of phospholipase A2 activity from a variety of sources.{14107}  

 

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SKU: 10008614 - 10 mg Category:

Description

The hydrochloride of leelamine, an inhibitor of pyruvate dehydrogenase kinase.

Formal name: 1R,2,3,4,4aS,9,10,10aR-octahydro-1,4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride

Synonyms:  Dehydroabietylamine

Molecular weight: 321.9

CAS: 16496-99-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors||Product Type|Biochemicals|Natural Products|Terpenes||Product Type|Biochemicals|Receptor Pharmacology||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors

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