A depside polyphenol antioxidant (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid

Lecanoric Acid – 1 mg

Brand:
Cayman
CAS:
480-56-8
Storage:
-20
UN-No:
Non-Hazardous - /

Lecanoric acid is a naturally occurring depside polyphenol isolated from a variety of lichens.{38091} It is a potent antioxidant, surpassing ascorbic acid in a 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging assay (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively).{38092} Lecanoric acid has antibacterial and antifungal activities with minimum inhibitory concentrations ranging from 0.5 to 1 mg/ml for a panel of fifteen microorganisms. In a cell viability assay, lecanoric acid exhibits antiproliferative activity against HeLa cells (IC50 = 123.97 μg/ml). Lecanoric acid also exhibits antidiabetic and hypolipidemic properties.{38091,38093}  

 

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Description

A depside polyphenol antioxidant (IC50s = 424.51 and 6.42 μg/ml for lecanoric and ascorbic acid, respectively in a DPPH assay); has antiproliferative (IC50 = 123.97 μg/ml against HeLa), antibacterial, and antifungal (MICs = 0.5-1 mg/ml for a panel of fifteen microorganisms) activities; exhibits antidiabetic and hypolipidemic properties

Formal name: 2,4-dihydroxy-6-methyl-benzoic acid, 4-carboxy-3-hydroxy-5-methylphenyl ester

Synonyms:  NSC 249981

Molecular weight: 318.3

CAS: 480-56-8

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Antifungals||Product Type|Biochemicals|Natural Products|Polyphenols||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases||Research Area|Infectious Disease|Fungal Diseases||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic

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