A potent inhibitor of EGFR-associated tyrosine kinase with an IC50 value of 0.012 µM that also inhibits pp60c-src(+) kinase and CamKII with IC50 values of 0.5 and 0.2 µM

Lavendustin C – 5 mg

Brand:
Cayman
CAS:
125697-93-0
Storage:
-20
UN-No:
Non-Hazardous - /

Lavendustin C, a derivative of a Streptomyces griseolavendus butyl acetate extract, is a potent inhibitor of epidermal growth factor (EGF) receptor-associated tyrosine kinase with an IC50 value of 0.012 µM.{16076} Lavendustin C also inhibits pp60c-src(+) kinase and Ca2+ calmodulin-dependent kinase II with IC50 values of 0.5 and 0.2 µM, respectively.{16078} At a concentration of 10-150 µM, lavendustin C inhibits tyrosine kinase-associated neutrophil degranulation and superoxide generation.{16077}  

 

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SKU: 10010329 - 5 mg Category:

Description

A potent inhibitor of EGFR-associated tyrosine kinase with an IC50 value of 0.012 µM that also inhibits pp60c-src(+) kinase and CamKII with IC50 values of 0.5 and 0.2 µM, respectively

Formal name: 5-[[(2,5-dihydroxyphenyl)methyl]amino]-2-hydroxy-benzoic acid

Synonyms:  HDBA|NSC 666251

Molecular weight: 275.3

CAS: 125697-93-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|EGFR/ErbB/HER Family||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|Growth Factor Receptors||Research Area|Immunology & Inflammation|Innate Immunity

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