A bioactive sphingolipid; reduces viability of human neutrophils in a concentration-dependent manner (1-50 μM); a precursor in the synthesis of lyso-ganglioside GM3

Lactosylsphingosine (d18:1) (synthetic) – 1 mg

Brand:
Cayman
CAS:
109785-20-8
Storage:
-20
UN-No:
Non-Hazardous - /

Lactosylsphingosine is a bioactive sphingolipid and a form of lactosylceramide (Item No. 16983) that is lacking the fatty acyl group. Lyso-lactosylceramide (1-50 μM) reduces viability of human neutrophils in a concentration-dependent manner.{38972} Unlike lactosylceramide, Lactosylsphingosine has no effect on protein synthesis and cell proliferation in cardiomyocytes.{38973} Lactosylsphingosine is a precursor in the synthesis of lyso-ganglioside GM3.{38974} [Matreya, LLC. Catalog No. 2088]  

 

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Description

A bioactive sphingolipid; reduces viability of human neutrophils in a concentration-dependent manner (1-50 μM); a precursor in the synthesis of lyso-ganglioside GM3,

Formal name: (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl 4-O-β-D-galactopyranosyl-β-D-glucopyranoside

Synonyms:  Lactosyl Sphingosine|Lyso-Lactosylceramide (synthetic)

Molecular weight: 623.8

CAS: 109785-20-8

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Lipid Biochemistry|Sphingolipids

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