A bioactive sphingolipid; synthetic stereoisomer of sphinganine (d18:0) and D-threo sphinganine (d18:0); induces autophagy in HCT116 cells (12 μM); induces cell cycle arrest of 7R4-LCB1 yeast cells; metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver

L-erythro Sphinganine (d18:0) – 1 mg

Brand:
Cayman
CAS:
6036-76-6
Storage:
-20
UN-No:
Non-Hazardous - /

L-erythro Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) (Item No. 10007945) and D-threo sphinganine (Item No. 24375).{40752} It induces autophagy in HCT116 cells when used at a concentration of 12 μM. L-erythro Sphinganine induces cell cycle arrest of 7R4-LCB1 yeast cells.{39518} It is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver.{40753} [Matreya, LLC. Catalog No. 1846]  

 

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SKU: 24374 - 1 mg Category:

Description

A bioactive sphingolipid; synthetic stereoisomer of sphinganine (d18:0) and D-threo sphinganine (d18:0); induces autophagy in HCT116 cells (12 μM); induces cell cycle arrest of 7R4-LCB1 yeast cells; metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver,

Formal name: 2R-amino-1,3S-octadecanediol

Synonyms:  C18 L-erythro Sphinganine (d18:0)|L-erythro Dihydrosphingosine

Molecular weight: 301.5

CAS: 6036-76-6

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Lipids|Sphingolipids||Research Area|Cancer|Autophagy||Research Area|Cell Biology|Cell Cycle||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking|Autophagy||Research Area|Lipid Biochemistry|Sphingolipids

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