A naturally-occurring amino acid which is a stable antioxidant; scavenges free radicals and oxidants

L-(+)-Ergothioneine – 5 mg

Brand:
Cayman
CAS:
497-30-3
Storage:
-20
UN-No:
Non-Hazardous - /

L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.{23678} Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-κB activation, and inhibits inflammatory gene expression.{23667,23665} In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine.{23667,23664,23668} Ergothioneine is transported by the organic cation/carnitine transporter 1, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.{23666}  

 

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Description

A naturally-occurring amino acid which is a stable antioxidant; scavenges free radicals and oxidants, controls NF-κB activation, and inhibits inflammatory gene expression; blocks oxidative DNA damage and cell death

Formal name: αS-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-inner salt-1H-imidazole-4-ethanaminium

Synonyms:  2-Mercaotohistidine betaine|NSC 7175

Molecular weight: 229.3

CAS: 497-30-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|DNA/RNA Oxidative Damage||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Non-enzymatic||Research Area|Oxidative Stress & Reactive Species|Reactive Sulfur

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