L-Biopterin is the oxidized form of BH4

L-Biopterin – 10 mg

Brand:
Cayman
CAS:
22150-76-1
Storage:
-20
UN-No:
Non-Hazardous - /

L-Biopterin is the oxidized form of tetrahydro-L-biopterin (BH4), a nitric oxide synthase (NOS) cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs).{15034} L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.{15033}  

 

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SKU: 10007662 - 10 mg Category:

Description

L-Biopterin is the oxidized form of BH4, a NOS cofactor. L-Biopterin can be reduced to BH4 via thioredoxin reductase followed by dihydropteridine reductase or reduced glutathione. It is extremely toxic to human melanocytes in culture (IC50 = 0.2 µM after 48 hrs).{15034} L-Biopterin is rarely found under physiological conditions except in the epidermis of patients with the depigmentation disorder Vitiligo.{15033}

Formal name: 2-amino-6-[(1R,2S)-1,2-dihydroxypropyl]-4(1H)-pteridinone

Synonyms:  L-erythro-Biopterin|NSC 339699

Molecular weight: 237.2

CAS: 22150-76-1

Purity: >98%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area

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