A synthetic glutamine dipeptide that can attenuate oxidative stress at doses of at doses of 0.75-1.5 mg/kg; reduces apoptosis in vitro; protects against inflammatory mediators

L-Alanyl-L-Glutamine – 100 g

Brand:
Cayman
CAS:
39537-23-0
Storage:
22
UN-No:
Non-Hazardous - /

L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg.{34399,34398,34396,34394} In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration.{34393} In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production.{34397} Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.{34395}  

 

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Description

A synthetic glutamine dipeptide that can attenuate oxidative stress at doses of at doses of 0.75-1.5 mg/kg; reduces apoptosis in vitro; protects against inflammatory mediators

Formal name: L-alanyl-L-glutamine

Synonyms:  Ala-Gln|L-Ala-L-Gln

Molecular weight: 217.2

CAS: 39537-23-0

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Peptides||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity

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