A high-affinity CB2 receptor-selective agonist (Kis = 6.4 and 1

L-759,633 – 10 mg

Brand:
Cayman
CAS:
174627-50-0
Storage:
-20
UN-No:
De Minimis - 1231 / 3

L-759,633 is a high-affinity peripheral cannabinoid receptor (CB2)-selective agonist with Ki values of 6.4 and 1,043 nM for CB2 and central cannabinoid (CB1) receptors, respectively. L-759,633 inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors with IC50 values of 8.1 nM and 10 µM, respectively.{13044}  

 

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SKU: 10009280 - 10 mg Category:

Description

A high-affinity CB2 receptor-selective agonist (Kis = 6.4 and 1,043 nM for CB2 and CB1, respectively); inhibits forskolin-stimulated cyclic AMP production in CHO cells transfected with CB2 or CB1 receptors (IC50s = 8.1 nM and 10 µM, respectively)

Formal name: 3-(1,1-dimethylheptyl)-6aR,7,10,10aR-tetrahydro-1-methoxy-6,6,9-trimethyl-6H-dibenzo[b,d]pyran

Synonyms: 

Molecular weight: 384.6

CAS: 174627-50-0

Purity: >98%

Formulation: A solution in methyl acetate

Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Neuroscience|Cannabinoid Research|CB1 & CB2 Receptors

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