Induces the differentiation of human pluripotent stem cells

KY 02111 – 50 mg

Brand:
Cayman
CAS:
1118807-13-8
Storage:
-20
UN-No:
Non-Hazardous - /

KY 02111 promotes the differentiation of human pluripotent stem cells to cardiomyocytes by inhibiting Wnt signaling.{24540} Treatment with 10 μM of KY 02111 has been shown to increase the ratio of beating cardiac colonies by 70–94% in cell aggregates of the embryonic stem cell lines KhES-1 and KhES-3 as well as the induced pluripotent stem cell lines 253G1, IMR90-1, IMR90-4, and RCHIPC0003.{24540}  

 

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Description

Induces the differentiation of human pluripotent stem cells, embryonic stem cells, or induced pluripotent stem cells to cardiomyocytes (10 μM) by inhibiting Wnt signaling

Formal name: N-(6-chloro-2-benzothiazolyl)-3,4-dimethoxy-benzenepropanamide

Synonyms: 

Molecular weight: 376.9

CAS: 1118807-13-8

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals||Research Area|Cardiovascular System|Heart|Cardiogenesis||Research Area|Cell Biology|Cell Signaling|Wnt Signaling||Research Area|Cell Biology|Stem Cell Research|Differentiation

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