Description
An inhibitor of XPO1/CRM1; reduces proliferation in a panel of patient-derived acute myeloid leukemia cells (IC50s = 100-500 nM); induces cell cycle arrest in the G1 phase and apoptosis in MOLT-4 T cell acute lymphoblastic leukemia cells and in a panel of six NSCLC cell lines
Formal name: 3-[3-[3-methoxy-5-(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl]-2Z-propenoic acid, 1-methylethyl ester
Synonyms:
Molecular weight: 355.3
CAS: 1333151-73-7
Purity: ≥98%
Formulation: A solid
Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis
