A tyrosinase inhibitor (IC50 = 30.6 µM); decreases growth of Leishmania parasites; protects mice from gamma irradiation-induced damage; used as a food additive

Kojic Acid – 50 g

Brand:
Cayman
CAS:
501-30-4
Storage:
-20
UN-No:
Non-Hazardous - /

Kojic acid is a fungal metabolite that inhibits tyrosinase, an enzyme involved in melanin synthesis, with an IC50 value of 30.6 µM for mushroom tyrosinase.{38117} It decreases growth of Leishmania parasites in vitro and in vivo, and it protects mice from damage induced by gamma irradiation.{38118,38119} Kojic acid has been used as a food additive to prevent enzymatic browning.{38116} Formulations containing kojic acid are used in the treatment of hyperpigmentation disorders.{21434}  

 

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Description

A tyrosinase inhibitor (IC50 = 30.6 µM); decreases growth of Leishmania parasites; protects mice from gamma irradiation-induced damage; used as a food additive,

Formal name: 5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Synonyms:  NSC 1942

Molecular weight: 142.1

CAS: 501-30-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antiparasitics|Antiprotozoals||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Parasitic Diseases|Leishmaniasis

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