An inhibitor of protein biosynthesis; inhibits isoleucine incorporation

Kirromycin – 1 mg

Brand:
Cayman
CAS:
50935-71-2
Storage:
-20
UN-No:
Non-Hazardous - /

Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis.{43956} It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli.{40951}  

 

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SKU: 25189 - 1 mg Category:

Description

An inhibitor of protein biosynthesis; inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis; inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli

Formal name: (αS,2R,3R,4R,6S)-N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-5-[(1E,3E,5E)-7-(1,2-dihydro-4-hydroxy-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrien-1-yl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadien-1-yl]-α-ethyltetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1E,3Z)-1,3-pentadien-1-yl-2H-pyran-2-acetamide

Synonyms:  NSC 316094

Molecular weight: 796.9

CAS: 50935-71-2

Purity: ≥95%

Formulation: A solid

Product Type|Biochemicals|Antibiotics||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Bacterial Diseases

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