A macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM); also acts as an endothelin receptor antagonist and has antiosteoporotic activities

Kendomycin – 100 µg

Brand:
Cayman
CAS:
183202-73-5
Storage:
-20
UN-No:
Non-Hazardous - /

Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM).{20722} It also acts as an endothelin receptor antagonist and has antiosteoporotic activities.{20722} Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins.  

 

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SKU: 11037 - 100 µg Category:

Description

A macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50 < 100 nM); also acts as an endothelin receptor antagonist and has antiosteoporotic activities

Formal name: (13E)-6R,7S,8R,9R,10,11,12S,15,16S,17,18S,19S-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-1,19:5R,9-diepoxybenzocyclooctadecen-3(5H)-one

Synonyms:  TAN 2162

Molecular weight: 486.6

CAS: 183202-73-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Product Type|Biochemicals|Xenobiotic Metabolites||Research Area|Cancer|Cell Death||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling

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