A selective PKD inhibitor (IC50s = 28.3

kb NB 142-70 – 50 mg

Brand:
Cayman
CAS:
1233533-04-4
Storage:
-20
UN-No:
Non-Hazardous - /

kb NB 142-70 is a selective inhibitor of protein kinase D (PKD) with IC50 values of 28.3, 58.7, and 53.2 nM for PKD1, 2, and 3, respectively.{32618} It has been shown to inhibit prostate cancer cell migration and invasion, as well as reduce wound healing in vitro.{32618,32619}  

 

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Description

A selective PKD inhibitor (IC50s = 28.3, 58.7, and 53.2 nM for PKD1, 2, and 3, respectively); inhibits prostate cancer cell migration and invasion, as well as reduces wound healing in vitro.

Formal name: 3,4-dihydro-9-hydroxy-[1]benzothieno[2,3-f]-1,4-thiazepin-5(2H)-one

Synonyms: 

Molecular weight: 251.3

CAS: 1233533-04-4

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|PKD & PKG||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cancer|Cell Migration & Metastasis||Research Area|Cancer|Cell Signaling|PKD Signaling

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