A broad spectrum antibiotic that alters translation by prokaryotic ribosomes

Kanamycin A (sulfate) – 5 g

Brand:
Cayman
CAS:
25389-94-0
Storage:
-20
UN-No:
Non-Hazardous - /

Kanamycin A is a broad spectrum antibiotic isolated from a soil streptomyces (S. kanamyceticus). This aminoglycoside alters translation by prokaryotic ribosomes, resulting in bacterial cell death.{25037} In molecular biology, kanamycin A is used as a selective agent to isolate transformants that are expressing a kanamycin resistance gene, usually neomycin phosphotransferase (NptII/neo). This mode of selection is most commonly used in plant and mammalian biology.  

 

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Description

A broad spectrum antibiotic that alters translation by prokaryotic ribosomes, resulting in bacterial cell death; used as a selective agent to isolate transformants that are expressing a kanamycin resistance gene, usually neomycin phosphotransferase (NptII/neo)

Formal name: O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine, monosulfate

Synonyms:  Ophtalmokalixan

Molecular weight: 582.6

CAS: 25389-94-0

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antibiotics|Aminoglycosides||Product Type|Biochemicals|Natural Products|Microbial Metabolites||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Plant Biology

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