A dietary flavonoid which has diverse physiological activities through both direct and indirect effects; directly binds ERα and ERβ

Kaempferol – 50 mg

Brand:
Cayman
CAS:
520-18-3
Storage:
-20
UN-No:
Non-Hazardous - 2811 / 6.1

Kaempferol is a flavonoid which is abundant in a variety of plant leaves and fruits. It has diverse physiological activities through both direct and indirect effects.{21135,20648} For example, kaempferol directly binds estrogen receptors α and β, acting as an inverse agonist or agonist.{21134,21136} It also acts as an antioxidant, which presumably contributes to its ability to suppress advanced glycation endproduct-induced NADPH oxidase, NF-κB signaling, and hypoxia-inducible factor-related angiogenesis and VEGF expression.{21137,21139} Kaempferol also suppresses signaling through certain receptor tyrosine kinases, including EGFR and HGF.{16737,21138,20648}  

 

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SKU: 11852 - 50 mg Category:

Description

A dietary flavonoid which has diverse physiological activities through both direct and indirect effects; directly binds ERα and ERβ, acting as an inverse agonist or agonist; acts as an antioxidant; suppresses signaling through certain receptor tyrosine kinases, including EGFR and HGF

Formal name: 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Synonyms:  Nimbecetin|NSC 407289|NSC 656277|Pelargidenon|Rhamnolutein|Swartziol|Trifolitin

Molecular weight: 286.2

CAS: 520-18-3

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Carbohydrate Oxidation

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