Description
An anti-inflammatory flavonoid; inhibits IL-1β-stimulated nitric oxide and PGE2 production in patient-derived osteoarthritis chondrocytes from 20-80 µg/ml; inhibits IL-1β-stimulated expression of NOS and COX-2 and activation of MAPK and NF-κB signaling; prevents the loss of E-cadherin, the expression of vimentin, and collagen type-1 production in hydrogen peroxide-exposed human bronchial epithelial cells from 1-20 µM; inhibits ear swelling, the production of IL-2 and IL-4, and reduces serum IgE levels in a mouse model of atopic dermatitis at 1.5 mg/kg; reduces production of ROS, collagen fiber deposition, and autophagosome formation in epithelial lung tissue of ovalbumin-challenged mice from 10-20 mg/kg
Formal name: 3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Synonyms: Astragalin|Kaempferol 3-β-D-glucopyranoside
Molecular weight: 448.4
CAS: 480-10-4
Purity: ≥98%
Formulation: A crystalline solid
Product Type|Biochemicals|Natural Products|Flavonoids||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Research Area|Immunology & Inflammation|Allergy||Research Area|Immunology & Inflammation|Arthritis (Non-autoimmune)||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen
