An antiviral agent; inhibits replication of SARS-CoV

K22 – 5 mg

Brand:
Cayman
CAS:
2141978-86-9
Storage:
-20
UN-No:
Non-Hazardous - /

K22 is an antiviral agent.{59568} It inhibits the replication of severe acute respiratory syndrome coronavirus (SARS-CoV), Middle East respiratory syndrome coronavirus (MERS-CoV), human coronavirus 229E (HCoV-229E), feline coronavirus (FCoV), and mouse hepatitis virus (MHV) in Vero cells when used at a concentration of 40 µM. K22 inhibits the formation of double membrane vesicles, a hallmark of coronavirus replication, and inhibits viral RNA synthesis in HCoV-229E-infected MRC-5 cells. It also reduces viral titers in cells infected with various Arteriviridae or Torovirinae viruses.{59569}  

 

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SKU: 31578 - 5 mg Category:

Description

An antiviral agent; inhibits replication of SARS-CoV, MERS-CoV, HCoV-229E, FCoV, and MHV in Vero cells at 40 µM; inhibits the formation of double membrane vesicles and viral RNA synthesis in HCoV-229E-infected MRC-5 cells; reduces viral titers in cells infected with various Arteriviridae or Torovirinae viruses

Formal name: N-[(1Z)-1-[[4-(4-bromophenyl)-4-hydroxy-1-piperidinyl]carbonyl]-2-phenylethenyl]-benzamide

Synonyms: 

Molecular weight: 505.4

CAS: 2141978-86-9

Purity: ≥98%

Formulation: A crystalline solid

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