A potent

JX-401 – 10 mg

Brand:
Cayman
CAS:
349087-34-9
Storage:
-20
UN-No:
Non-Hazardous - /

JX-401 is a potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM).{27632} It does not inhibit the p38γ isoform.{27632} JX-401 is effective in mammalian cells, as it blocks the differentiation of myoblasts into myotubes.{27632}  

 

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Description

A potent, reversible inhibitor of the p38α isoform of MAP kinase (IC50 = 32 nM) that does not inhibit the p38γ isoform

Formal name: [2-methoxy-4-(methylthio)phenyl][4-(phenylmethyl)-1-piperidinyl]-methanone

Synonyms:  p38 MAPK Inhibitor VI|p38 Mitogen-activated Protein Kinase Inhibitor VI

Molecular weight: 355.5

CAS: 349087-34-9

Purity: ≥95%

Formulation: A crystalline solid

Product Type|Biochemicals|Kinase Inhibitors|p38 MAPK||Product Type|Biochemicals|Small Molecule Inhibitors|Kinases||Research Area|Cell Biology|Cell Signaling|p38 MAPK Signaling

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