An internal standard for the quantification of JWH 015 by GC- or LC-MS

JWH 015-d7 – 500 µg

Brand:
Cayman
CAS:
1346601-16-8
Storage:
-20
UN-No:
Non-Hazardous - /

JWH 015-d7 contains seven deuterium atoms at the 1, 1′, 2, 2′, 3, 3, and 3 positions. It is intended for use as an internal standard for the quantification of JWH 015 by GC- or LC-mass spectrometry (MS). JWH 015 is a selective aminoalkylindole peripheral cannabinoid (CB2) receptor agonist with Ki values of 13.8 and 383 nM for human recombinant CB2 and CB1 receptors, respectively.{7912} Using Theiler’s murine encephalomyelitis virus as a model for human multiple sclerosis, treatment with WIN 55,212-2, ACEA, and JWH 015 significantly improved the neurological deficit of established disease.{14364} JWH 015 was shown to reduce microglial activation, abrogate antigen expression, and decrease the number of CD4+ infiltrating T-cells in the spinal cord. In addition, JWH 015 reduces IFN-γ-induced up-regulation of CD40 expression in mouse microglial cells by interfering with the JAK/STAT1 pathway.{14363}  

 

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SKU: 10660 - 500 µg Category:

Description

An internal standard for the quantification of JWH 015 by GC- or LC-MS

Formal name: (2-methyl-1-propyl-(1,1,2,2,3,3,3-d7)-1H-indol-3-yl)-1-naphthalenyl-methanone

Synonyms: 

Molecular weight: 334.5

CAS: 1346601-16-8

Purity: ≥99% deuterated forms (d1-d7)

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Drugs of Abuse||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Research Area|Forensic Chemistry & Toxicology|Cannabinoids|Synthetic Cannabinoids

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