(+)-JQ1 PA – 5 mg

Brand:
Cayman
CAS:
2115701-93-2
Storage:
-20
UN-No:
Non-Hazardous - /

(+)-JQ1 PA is a clickable form of the bromodomain and extraterminal domain (BET) inhibitor (+)-JQ1 (Item Nos. 11187 | 9002910).{35056} (+)-JQ1 PA binds to bromodomain-containing protein 4 (BRD4) and displaces it from Myc in a ChIP-qPCR assay. It reduces proliferation of MV4-11 cells (IC50 = 10.4 nM).  

 

Available on backorder

SKU: 30414 - 5 mg Category:

Description

A clickable form of (+)-JQ1; binds to BRD4 and displaces it from Myc in a ChIP-qPCR assay; reduces proliferation of MV4-11 cells (IC50 = 10.4 nM)


Formal name: (6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-N-2-propyn-1-yl-6H -thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide

Synonyms: 

Molecular weight: 437.9

CAS: 2115701-93-2

Purity: ≥98%

Formulation: A crystalline solid