A macrolide antibiotic; active against clinical isolates of the Gram-positive aerobic bacteria (MIC50s = ≤0.39 µg/ml for all)

Josamycin – 25 mg

Brand:
Cayman
CAS:
16846-24-5
Storage:
-20
UN-No:
Non-Hazardous - /

Josamycin is a macrolide antibiotic originally isolated from S. narbonensis.{53265} It is active against clinical isolates of the Gram-positive aerobic bacteria S. aureus, S. epidermidis, S. pneumoniae, S. pyogenes, and S. agalactiae (MIC50s = ≤0.39 µg/ml for all), as well as the Gram-negative anaerobic bacteria Peptococcus, Peptostreptococcus, and Clostridium when used at concentrations of 6.25 µg/ml.{53266} It increases survival in mouse models of systemic S. aureus, S. pyogenes, and S. pneumoniae infection with ED50 values of 206.8, 205, and 86.7 mg/kg, respectively.{53267}  

 

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SKU: 29606 - 25 mg Category:

Description

A macrolide antibiotic; active against clinical isolates of the Gram-positive aerobic bacteria (MIC50s = ≤0.39 µg/ml for all), as well as Gram-negative anaerobic bacteria at 6.25 µg/ml; increases survival in mouse models of systemic S. aureus, S. pyogenes, and S. pneumoniae infection (ED50s = 206.8, 205, and 86.7 mg/kg, respectively)

Formal name: 3-acetate 4B-(3-methylbutanoate) leucomycin V

Synonyms:  Kitasamycin A3|Leucomycin A3|Turimycin A5

Molecular weight: 828

CAS: 16846-24-5

Purity: ≥98%

Formulation: A solid

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