A bacterial pyridone metabolite that inhibits NOS activity

Iromycin A – 500 µg

Brand:
Cayman
CAS:
213137-53-2
Storage:
-20
UN-No:
Non-Hazardous - /

Iromycin A is a bacterial pyridone metabolite that inhibits nitric oxide synthase (NOS) activity, with selectivity for NOS III (endothelial NOS) over NOS I (neuronal NOS).{31289,31290} Iromycin metabolites and derivatives block NADH oxidation in beef heart submitochondrial particles (IC50 = 0.461 µM for iromycin A).{31291}  

 

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SKU: 19621 - Category:

Description

A bacterial pyridone metabolite that inhibits NOS activity, with selectivity for NOS III (eNOS) over NOS I (nNOS)

Formal name: 6-[(2E,5E)-3,7-dimethyl-2,5-octadien-1-yl]-4-hydroxy-3-methyl-5-propyl-2(1H)-pyridinone

Synonyms:  NK 26588

Molecular weight: 303.4

CAS: 213137-53-2

Purity: ≥98%

Formulation: A solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Research Area|Cell Biology|Cell Signaling|Nitric Oxide Signaling||Research Area|Cell Biology|Mitochondrial Biology

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