Description
Inositol hexakisphosphate kinase 2 (IP6K2) is a cytoplasmic kinase that catalyzes the conversion of IP6 to diphosphoinositol pentakisphosphate in the presence of ATP.{22131} IP6K2 functions as a proapoptotic protein kinase.{22130} IP6K2 binds to tumor necrosis factor receptor-associated factor 2 and inhibits NF-κB signaling.{22139} Heat Shock Protein 90 regulates apoptosis through a normal physiological interaction with IP6K2 by inhibiting its catalytic activity.{22128} Thus, IP6K2 is a potential target for cancer therapeutics development.{22128}
Synonyms: IHPK2|Inositol Hexakisphosphate Kinase 2
Immunogen: Human IP6K2 protein
Formulation: 200 µg lyophilized protein A-purified monoclonal antibody
Isotype: IgG2b
Applications: ICC and WB
Origin:
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Cell Biology|Cell Signaling|NF-κB Signaling||Research Area|Epigenetics, Transcription, & Translation|Transcription Factors
