Description
Prostaglandin I2 (PGI2) is a potent vasorelaxant and inhibitor of human platelet aggregation.{4375} Research of the PGI2 receptor (IP receptor) also demonstrates its participation in signal transduction of the pain response, cardioprotection, and inflammation.{9050,5018,9805,8508,5466} Cloning of the mouse and human IP receptors reveals a significant amino-terminal truncation of the human IP receptor compared to the mouse receptor.{3173,1614} Accordingly, this antibody is useful only for immunochemical analysis of mouse and rat samples. The IP receptor (mouse) polyclonal antibody detects a ~45 kDa band from several human cell lines. Additionally, a 67 kDa band may be observed from mouse neural tissues and platelets. The calculated molecular weight of the IP receptor (mouse) is 44 kDa based on the amino acid sequence.
Synonyms: PGI2 Receptor|Prostacyclin Receptor|Prostaglandin I2 Receptor
Immunogen: Peptide from the N-terminal region of mouse IP receptor
Formulation: 500 µl of peptide affinity-purified antibody
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Blood|Coagulation & Hemostasis||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway
