Description
Prostaglandin I2 (PGI2) is a potent vasorelaxant and inhibitor of human platelet aggregation.{4375} The PGI2 receptor (IP receptor) also participates in signal transduction of the pain response, cardioprotection, and inflammation.{9050,5018,9805,8508,5466} Cloning of the murine and human IP receptors revealed a significant amino-terminal truncation of the human IP receptor compared to the murine receptor.{3173,1614} Cayman Chemical’s IP receptor antibody detects a 67 kDa band on immunoblot. The predicted migration of the deglycosylated protein is 40 kDa and bands at either 67 or 40 kDa may be detected depending on the degree of post-translational modification of the sample.{11563}
Synonyms: PGI2 Receptor|Prostacyclin Receptor|Prostaglandin I2 Receptor
Immunogen: Synthetic peptide from the N-terminal region of human IP receptor
Formulation: 500 µl of peptide affinity-purified antibody
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cardiovascular System|Heart||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Neuroscience|Pain Research
