A contrast reagent; induces inhibition of electrical activity but has no excitatory effect in rat hippocampal slices and lacks any effect on ventral root flexes of feline spinal cord

Iohexol – 10 g

Brand:
Cayman
CAS:
66108-95-0
Storage:
-20
UN-No:
Non-Hazardous - /

Iohexol is a non-ionic and water-soluble contrast agent.{36313} It induces inhibition of electrical activity but has no excitatory effect in vitro in rat hippocampal slices and lacks any effect in vivo on ventral root flexes of feline spinal cord, indicating minimal neurotoxicity. Iohexol also induces a smaller decrease in contractile force than the ionic and high osmolarity contrast agent metrizoate in isolated rabbit hearts perfused with a 350 mg/ml solution.{36312} Formulations containing iohexol have been used for visualization of arteries, veins, the urinary tract, and joints using X-ray and computed tomography (CT) scan imaging techniques.  

 

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Description

A contrast reagent; induces inhibition of electrical activity but has no excitatory effect in rat hippocampal slices and lacks any effect on ventral root flexes of feline spinal cord, indicating minimal neurotoxicity; induces a smaller decrease in contractile force than metrizoate in isolated rabbit hearts perfused with a 350 mg/ml solution

Formal name: 5-[acetyl(2,3-dihydroxypropyl)amino]-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide

Synonyms: 

Molecular weight: 821.1

CAS: 66108-95-0

Purity: ≥98% (mixture of isomers)

Formulation: A crystalline solid

Product Type|Biochemicals|Labeling & Detection|Dyes, Stains, & Indicators||Research Area|Cardiovascular System|Heart|Myocardial Contractility||Research Area|Cardiovascular System|Vasculature

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