A selective COX-2 inhibitor (IC50s = 0.03 and 0.36 µM for COX-2 and COX-1

Inotilone – 5 mg

Brand:
Cayman
CAS:
906366-79-8
Storage:
-20
UN-No:
Non-Hazardous - /

Inotilone is a cyclooxygenase (COX) inhibitor found in mushrooms of Phellinus and Inonotus sps. that inhibits COX-2 over COX-1 with IC50 values of 0.03 and 0.36 µM, respectively.{14795,14796} It is a poor inhibitor of hydroxysteroid dehydrogenase and xanthine oxidase (IC50s = 50.4 and 9.1 µM, respectively).{14795,14796} Inotilone demonstrates anti-inflammatory, antiviral, and antioxidant effects in various experimental models.{32528,32529,32530}  

 

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SKU: 10010089 - 5 mg Category:

Description

A selective COX-2 inhibitor (IC50s = 0.03 and 0.36 µM for COX-2 and COX-1, respectively)

Formal name: (2Z)-2-[(3,4-dihydroxyphenyl)methylene]-5-methyl-3(2H)-furanone

Synonyms: 

Molecular weight: 218.2

CAS: 906366-79-8

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Antivirals||Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Ox Stress Reagents|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Infectious Disease|Viral Diseases||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Oxygen|Xanthine Oxidase

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