Description
Nitric Oxide Synthase (NOS) catalyzes the biosynthesis of nitric oxide from L-arginine. Constitutively expressed NOS is found in brain (nNOS) and endothelial cells (eNOS). iNOS is a soluble enzyme found in a variety of tissues including macrophages, hepatocytes, vascular smooth muscle cells, and chondrocytes.{1243,4141} iNOS expression is increased by a variety of factors including LPS, IFN-γ, Il-1β, and TNF-α, whereas expression is deceased by dexamethasone.{1904,1970,2111,3440,4851} The enzyme has been cloned from several species including mouse, rat, and human with homology of at least 80% between these species.{4141} The calculated molecular weight of the protein from the deduced amino acid sequence is 130,000 – 131,000.{1243}
Synonyms: Inducible Nitric Oxide Synthase|NOS II
Immunogen: Purified iNOS from cytokine-induced mouse macrophages (RAW 264.7) cells
Formulation: 500 μl of Protein A-purified antibody
Isotype:
Applications: IHC, IP, and WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Immunohistochemistry||Application|Immunoprecipitation||Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen
