An internal standard for the quantification of indomethacin by GC- or LC-MS

Indomethacin-d4 – 500 µg

Brand:
Cayman
CAS:
87377-08-0
Storage:
22
UN-No:
De Minimis - 2811 / 6.1

Indomethacin-d4 is intended for use as an internal standard for the quantification of indomethacin (Item No. 70270) by GC- or LC-MS. Indomethacin is a non-selective COX inhibitor (IC50s = 1.67 and 24.6 µM for human COX-1 and COX-2, respectively).{1286} It reduces filter paper-disc induced growth of granulation tissue, a marker of inflammation, in chick chorioallantoic membranes.{37630} Indomethacin reduces ocular inflammation induced by bovine serum in rabbits.{37631} It also reduces paw edema in a rat model of carrageenan-induced inflammation.{37632}  

 

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SKU: 25434 - 500 µg Category:

Description

An internal standard for the quantification of indomethacin by GC- or LC-MS

Formal name: 1-(4-chlorobenzoyl-2,3,5,6-d4)-5-methoxy-2-methyl-1H-indole-3-acetic acid

Synonyms: 

Molecular weight: 361.8

CAS: 87377-08-0

Purity: ≥99% deuterated forms (d1-d4)

Formulation: A solid

Application|Mass Spectrometry||Product Type|Biochemicals|Analytical Standards||Product Type|Biochemicals|Isotopically Labeled Standards|Deuterium||Product Type|Biochemicals|Small Molecule Inhibitors|Cyclooxygenases||Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Immunology & Inflammation|Inflammatory Lipid Mediators|Prostaglandins||Research Area|Lipid Biochemistry|Cyclooxygenase Pathway

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