(-)-Indolactam V – 500 µg

Brand:
Cayman
CAS:
90365-57-4
Storage:
4
UN-No:
Non-Hazardous - /

(−)-Indolactam V is a tumor-promoting teleocidin compound that activates protein kinase C (PKC). It binds to PKC regulatory domains of mouse skin PKCη and rat brain PKCγ with Ki values of 3.4 nM and 1 μM, respectively.{23150,23151} At 1 μM, (−)-indolactam V induces differentiation of human embryonic stem cells into pancreatic progenitors through activation of PKC signaling.{23152}  

 

SKU: - Category:

Description

A tumor-promoting teleocidin compound that activates PKC (Ki = 3.4 nM and 1 μM for PKCη and PKCγ, respectively); induces differentiation of human embryonic stem cells into pancreatic progenitors


Formal name: (2S,5S)-1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-3H-pyrrolo[4,3,2-gh]-1,4-benzodiazonin-3-one

Synonyms: 

Molecular weight: 301.4

CAS: 90365-57-4

Purity: ≥95%

Formulation: A solid


Product Type|Biochemicals|Small Molecule Activators|Kinases||Research Area|Cell Biology|Stem Cell Research|Differentiation