Immunogen: Mouse IgG • Host: Goat • Species Reactivity: (+) Mouse • Cross Reactivity: (+) Mouse IgG1

IgG Fab (mouse) Monoclonal Antibody – 100 µg

Brand:
Cayman
Storage:

Immunoglobulin G (IgG) is a member of the immunoglobulin superfamily of glycoproteins that plays a central role in the adaptive immune response.{28520} It is produced by B cells and later secreted by plasma cells and is the most abundant circulating antibody in human and mouse serum.{28520,55170,55174} IgG consists of two heavy chains of approximately 50 kDa each and two light chains of approximately 25 kDa each.{28520} The heavy chains are linked together by disulfide bonds to form an Fc region and also combine with the light chains to form the Fab region, which mediate receptor and antigen binding, respectively.{55171} IgG is produced following IgM class-switching in response to infection and is involved in numerous humoral host defense responses, including antibody-dependent cell-mediated cytotoxicity (ADCC), toxin neutralization, and pathogen opsonization.{55170} IgG exists as four isotypes in mice: IgG1, IgG2b, IgG3, and, in a strain-specific manner, IgG2a or IgG2c.{55172,53858} Formulations containing humanized, chimeric, or murine IgG monoclonal antibodies have been used in the treatment of inflammatory diseases, such as ulcerative colitis, rheumatoid arthritis, and asthma, as well as cancer.{55173} Cayman’s IgG Fab (mouse) Monoclonal Antibody can be used for ELISA, flow cytometry (FC), and immunoprecipitation (IP) applications. The antibody recognizes the Fab region of IgG from mouse samples.  

 

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SKU: 21780 - 100 µg Category:

Description

Immunogen: Mouse IgG • Host: Goat • Species Reactivity: (+) Mouse • Cross Reactivity: (+) Mouse IgG1, IgG2a, IgG2b, IgG3; (-) Mouse IgM, IgA, IgE; (-) Human, rabbit, rat IgG • Applications: ELISA, FC, IP

Synonyms: Immunoglobulin G

Immunogen: Mouse IgG

Formulation: 100 µg of protein G affinity-purified monoclonal antibody

Isotype: IgG

Applications: ELISA, FC, IP

Origin:

Stability: 365 days

Application|ELISA||Application|Flow Cytometry||Application|Immunoprecipitation||Product Type|Antibodies|Monoclonal Antibodies||Research Area|Cancer||Research Area|Cardiovascular System|Blood|Serum Proteins||Research Area|Immunology & Inflammation|Adaptive Immunity||Research Area|Immunology & Inflammation|Autoimmunity|Rheumatoid Arthritis||Research Area|Immunology & Inflammation|Gastric Disease|Ulcerative Colitis||Research Area|Immunology & Inflammation|Pulmonary Diseases|Asthma||Research Area|Infectious Disease

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