A synthetic ω-3 PUFA that resists β-oxidation and complex lipid incorporation

Icosabutate – 500 µg

Brand:
Cayman
CAS:
1253909-57-7
Storage:
-20
UN-No:
De Minimis - 1170 / 3

Icosabutate is a synthetic ω-3 polyunsaturated fatty acid derived from eicosapentaenoic alcohol and 2-bromo butyric acid. It was designed to resist β-oxidation and complex lipid incorporation and increase efficacy in fatty acid-responsive intracellular signaling systems.{30867,33833} In a clinical trial, oral administration of icosabutate (600 mg) significantly reduced triglyceride, very low-density lipoprotein cholesterol, and Apo c-III levels in patients with very high triglyceride levels.{30867,33833}  

 

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Description

A synthetic ω-3 PUFA that resists β-oxidation and complex lipid incorporation, increasing efficacy in FA-responsive intracellular signaling systems

Formal name: 2-[(5Z,8Z,11Z,14Z,17Z)-5,8,11,14,17-eicosapentaen-1-yloxy]-butanoic acid

Synonyms:  PRB 01022|PRC 4016

Molecular weight: 374.6

CAS: 1253909-57-7

Purity: ≥95%

Formulation: A solution in ethanol

Product Type|Biochemicals|Lipids|Fatty Esters/Ethers||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Lipid Biochemistry|Fatty Acids

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