A potent

ICI 118551 (hydrochloride) – 10 mg

Brand:
Cayman
CAS:
72795-01-8
Storage:
22
UN-No:
Non-Hazardous - /

ICI 118551 is a potent, selective antagonist of the β2-adrenergic receptor (Ki = 0.7 nM for the β2 receptor, compared with 49.5 and 611 nM for β1 and β3 receptors, respectively).{25395,25151} It is active in vivo and is often used to evaluate the actions of adrenergic receptor agonists.{25421,23875,25153}  

 

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Description

A potent, selective antagonist of the β2-adrenergic receptor (Ki = 0.7 nM for the β2 receptor, compared with 49.5 and 611 nM for β1 and β3 receptors, respectively); active in vivo and often used to evaluate the actions of adrenergic receptor agonists

Formal name: (2R,3R)-rel-1-[(2,3-dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol, monohydrochloride

Synonyms: 

Molecular weight: 313.9

CAS: 72795-01-8

Purity: ≥99%

Formulation: A crystalline solid

Product Type|Biochemicals|Receptor Pharmacology|Antagonists||Research Area|Cardiovascular System|Heart|Myocardial Contractility

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