Description
I2PP2A/SET is a multitasking protein, involved in apoptosis, transcription, nucleosome assembly, and histone binding. The SET gene produces two isoforms from transcript variants. Isoform 1 and 2 interact directly with each other and with ANP32A within the tripartite inhibitor of acetyltransferases (INHAT) complex, inhibiting EP300/CREBBP and PCAF-mediated acetylation of histones. The two isoforms differ in their amino termini but are identical through the regions used as antigens for preparing this antibody.
Synonyms: Inhibitor of granzyme A-activated DNase|PHAPII|Phosphatase 2A Inhibitor|Template-Activating Factor I
Immunogen: synthetic peptides from human I2PP2A/SET amino acids 79-94 and 148-164
Formulation: 100 µl of protein G-purified IgG in 200 µl PBS containing 0.02% sodium azide and 0.1 mg/ml BSA
Isotype:
Applications: WB
Origin: Animal/Rabbit
Stability: 365 days
Application|Western Blot||Product Type|Antibodies|Polyclonal Antibodies||Research Area|Cell Biology|Cell Death|Apoptosis||Research Area|Epigenetics, Transcription, & Translation|RNA, DNA, & Protein Synthesis||Research Area|Epigenetics, Transcription, & Translation|Writers|Histone Acetylation
