An active principle of P. amarus that has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity

Hypophyllanthin – 1 mg

Brand:
Cayman
CAS:
33676-00-5
Storage:
-20
UN-No:
Non-Hazardous - /

Hypophyllanthin is an active principle of P. amarus, a plant studied for its potential to treat hepatotoxicity.{28462} In Caco-2 cells 100 µM hypophyllanthin has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity.{28463}  

 

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SKU: 11715 - 1 mg Category:

Description

An active principle of P. amarus that has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity

Formal name: (7S,8S,9R)-9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-naphtho[1,2-d]-1,3-dioxole

Synonyms:  NSC 619044

Molecular weight: 430.5

CAS: 33676-00-5

Purity: ≥98%

Formulation: A crystalline solid

Product Type|Biochemicals|Natural Products||Product Type|Biochemicals|Transporter & Exchanger Modulators||Research Area|Toxicology|Drug Metabolism

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