A secondary bile acid; decreases plasma VLDL and LDL cholesterol levels and reduces fasting glucose levels and atherosclerotic lesion size in LDL receptor knockout mice fed a Western diet at 1.25% in the diet; serum levels are increased in patients with Crohn’s disease or ulcerative colitis

Hyodeoxycholic Acid – 25 g

Brand:
Cayman
CAS:
83-49-8
Storage:
-20
UN-No:
Non-Hazardous - /

Hyodeoxycholic acid (HDCA) is a secondary bile acid.{33390} It is produced from lithocholic acid (Item No. 20253) by gut bacteria.{33390,33392,33395} Dietary administration of HDCA (1.25% w/w) decreases plasma VLDL and LDL cholesterol levels and reduces fasting glucose levels and atherosclerotic lesion size in LDL receptor knockout mice fed a Western diet.{33393} Serum levels of HDCA are increased in patients with Crohn’s disease or ulcerative colitis.{33391}  

 

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Description

A secondary bile acid; decreases plasma VLDL and LDL cholesterol levels and reduces fasting glucose levels and atherosclerotic lesion size in LDL receptor knockout mice fed a Western diet at 1.25% in the diet; serum levels are increased in patients with Crohn’s disease or ulcerative colitis

Formal name: (5β)-3α,6α-dihydroxy-cholan-24-oic acid

Synonyms:  HDCA|NSC 60672|α-Hyodeoxycholic Acid

Molecular weight: 392.6

CAS: 83-49-8

Purity: ≥90%

Formulation: A crystalline solid

Application|Mass Spectrometry||Product Type|Biochemicals|Lipids|Sterol Lipids||Research Area|Cardiovascular System|Cardiovascular Diseases|Atherosclerosis||Research Area|Cardiovascular System|Lipids & Lipoproteins|Lipoproteins||Research Area|Endocrinology & Metabolism|Bile Acids & Microbiome||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Diabetes||Research Area|Endocrinology & Metabolism|Metabolic Diseases|Dyslipidemias||Research Area|Immunology & Inflammation|Gastric Disease|Crohn’s Disease||Research Area|Immunology & Inflammation|Gastric Disease|IBS

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